Thai Journal of Gastroenterology

Article :
Feasibility of Fujinon Intelligent Color Enhancement (FICE) with Magnification in Differentiating between Diminutive Adenomatous and Hyperplastic Polyps

Author :
Sripatoorat P
Hongthanakorn C
Angchuan S

Abstract :
Background: In Thailand, there are limited data describing the performance of FICE with high magnification for differentiating polyp histology during colon cancer screening. The objective of this study was to evaluate the feasibility of FICE with high magnification for the differentiation of diminutive hyperplastic and adenomatous polyps by using pit patterns observed during real-time colon cancer screeningy at Bhumibol Adulyadej Hospital. Patients and Methods: The subjects were 200 patients who underwent colon cancer screening. Pit patterns were applied to predict the histology of 358 polyps which less than 0.6 cm using FICE with high magnification. The feasibility of FICE were calculated and compared with the histopathology as a gold standard. Results: FICE with high magnification showed sensitivity of 78.7%, specificity of 86.2%, accuracy of 82.1%, PPV of 87.6% and NPV of 76.6% for the discrimination of hyerplastic and adenomatous polyps less than 0.6 cm. Conclusion: FICE with high magnification provided the acceptable validity scores for discrimination of diminutive polyp histology during colon cancer screening.

Keyword :
Fujinon Intelligent Color Enhancement (FICE), diminutive polyps.

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