Abstract :
Background & Aims: Antiplatelets drugs are widely used and may cause GI complications. This
study was aimed at assessing the incidence and the risk factors of antiplatelet-induced gastrointestinal (GI) complication.
Methods: Patients ≥ 18 years old with newly diagnosed coronary artery disease who were admitted for
coronary angiography at Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand, between January 1, 2010
and December 31, 2012 were included for study. The GI complications were classified as the CSULGIE composite
end points.
Results: Of 729 patients, 66 developed gastrointestinal complications (9.05%; 6.03 events per 100 patient-
years), of which clinically significant anemia of presumed occult GI origin was most common (44 cases,
66.7%). Patients with GI complications were more often re-hospitalized. No significant risk factors for the occurrence
of GI complications were identified.
Conclusion: Clinically significant anemia of presumed occult GI origin was the most common gastrointestinal
complication in patients receiving antiplatelet therapy in Maharaj Nakorn Chiang Mai hospital. |
file/Thai-Journal-of-gastroenterology-vol-15-no-3-953438.pdf