Abstract :
Background: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder . Patients may
suffer from abdominal discomfort, bloating or pain associated with disturbed defecation. The etiology has not been
clear. Colonic diverticula are mucosal outpouchings through the large bowel. Recent study demonstrated more
prevalence of diverticulosis in IBS.
Aim: To determine the prevalence of diverticulosis in IBS patients and the association between diverticulosis
and IBS patients.
Method: We enrolled 150 patients in IBS group (75 patients) and control group (75 patients). IBS was
defined by Rome III criteria. Medical history, physical examination and colonoscopy was done.
Results: The IBS group consisted of 29 males and 46 females with a mean age of 54 years.The characteristics
of abdominal pain in IBS were described as fullness and bloating in 96%. The frequencies of symptom
occurring per month were 36% had 3-7 days, 62.7% had 8-14 days, and 1.3% had 8-14 days. Comparison of the
IBS and control groups, there was no significant difference in age, gender and BMI between IBS group and control
group (p > 0.05). The prevalence of colonic diverticulum of IBS group was 24.0% and control group was 10.7%.
There was statistically significant difference in prevalence between both groups (p value = 0.031). Comparison of
location of diverticulum, right sided colon and cecum diverticula were mostly found in IBS group and in control
group were found in rectosigmoid and along colon colon.There was no significant difference in location of diverticulum
between both groups (p value = 0.149).There was no significant difference in numbers of diverticula
between both groups (p value = 0.095).
Conclusions: Prevalence of diverticulosis in IBS group was more than in control group and these diseases
may be similar in pathogenesis that should be studied more extensively especially in elderly patients. |
file/Thai-Journal-of-gastroenterology-vol-10-no-3-2901213.pdf