Cytomegalovirus (CMV) infection of the gastrointestinal tract in an immunocompetent host is an uncommon
condition. It can involve any part of the intestinal tract, but more commonly at the colon. Extensive small
bowel involvement is rather uncommon. We report a case of jejunal perforation due to spontaneous reactivation of
latent CMV infection in an immunocompetent host. He was a 75-year-old healthy male presented with chronic
abdominal pain for 2 months which physical examination revealed signs of localized peritonitis at upper abdomen.
After surgical laparotomy, resection of perforated jejunal segment was performed. Histologic study and anti-CMV
IgG were in consistent with the diagnosis of CMV jejunitis. He was subsequently treated successfully with a
2-weeks course of intravenous ganciclovir. After 6 months of follow-up period, he was relatively fit and uneventful.
file/Thai-Journal-of-gastroenterology-vol-8-no-2-4288225.pdf