Abstract :
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm in the gastrointestinal tract. GIST is a group of mesenchymal tumors that predominantly exhibit an altered oncogene, KIT (CD 117). There are imaging features and pattern of spreading be suggestive of GISTs diagnosis such as the appearances of a large exophytic bowel mass with necrosis or hemorrhage, hypervascular liver metastases, and smooth low-density mesenteric masses. Adenopathy, concentric bowel involvement, large-volume ascites, and spiculated mesenteric masses suggest an alternative diagnosis. The radiologic appearances can change dramatically after therapy which solid hypervascular masses previously may become completely cystic on CT even within 1 month of treatment. After initial successful treatment; tumor enlargement, new sites of tumor, and/or a new nodule within a stable masses are indicators of progression of disease.
[Thai J Gastroenterol 2005; 6(2): 105-110] |
file/Thai-Journal-of-gastroenterology-vol-6-no-2-4522310.pdf