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Thai Journal of Gastroenterology

Thai Journal of Gastroenterology

2006 Vol.7 No.3

Article :
Survival Analysis of Hilar Cholangiocarcinoma Treated by Endoscopic Biliary Drainage at Srinagarind Hospital, Khon Kaen, Thailand


Author :
Arthit Wongsaensook
Wattana Sukeepaisarnjaroen
Pisaln Mairiang
Kitti Chunlertrith
Apichat Sangchan
Vallop Laopiboon
Eimorn Mairiang


Abstract :

Cholangiocarcinoma (CHCA) is a major common problems in the northeastern region of Thailand. Be-
cause the diagnosis is usually made at a late stage, palliative treatment is often the treatment of choice.  Internalstent biliary drainage is accepted as a good palliative treatment.  The objective of this study was to analyse the survival of hilar CHCA patients treated by internal stent biliary drainage.  A retrospective review was made involvst ing CHCA patients at Srinagarind Hospital, Khon Kaen, Thailand.  Data were collected from 1  January 2001 to st 31  December 2004.  The outcomes of patients were assessed up to 30th June 2005, or to the time of death. Survival analysis was performed.  Fifty-five patients were enrolled. The overall median survival rate was 64 days (95% CI = 48-91) with the cumulative 30, 90 and, 150 days survival rates of 78%, 40% and, 24% respectively. There were 2 types of CHCA, ERCP1 (or Bismuth I) and ERCP2 (equal or higher than Bismuth II).  The median survival rates for ERCP 1 at 30, 60 and, 90 days were not different from those of ERCP2.  The overall median survival rates were 82 days (95% CI = 33-101) in ERCP 1 and 57 days (95% CI = 34-83) in ERCP2.  The ultimate outcome of patients with CHCA was poor despite of the palliative treatment.

[Thai J Gastroenterol 2006; 7(3): 132-136]


Keyword :
hilar cholangiocarcinoma, opisthorchis viverrini, jaundice, biliary drainage


PDF Download :
file/Thai-Journal-of-gastroenterology-vol-7-no-3-633323.pdf

 



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