Abstract :
Patients who suffered from PL can present as many ways such pseudocyst, ascites or pleural effusion. Identifying the cause is not as important as detailing pancreatic duct anatomy and disrupted site. Patient with low output leak usually has side branch disruption. They also respond well to conventional therapy. Generally, octreotide will speed up healing process of PL and work as a good adjunct to conventional therapy. Patient with partial duct disruption may not heal by conventional therapy alone. Recently endoscopic therapy along with ERP has become a standard of care in a group who fail conventional therapy. Unfortunately patients with duct disconnection and/or leakage at the time will not respond to non-surgical management. Therefore, surgery is the main salvage therapy in this group of patients.
[Thai J Gastroenterol 2005; 6(3): 154-157] |