Abstract :
Cytomegalovirus infection occurs in immunocompromised patients or previously treated with systemic corticosteroids or immunosuppressant. However, CMV infection may occurs in immunocompetent patients, which is recognized as rare condition. We report a case of cytomegalovirus (CMV) colitis in case of steroid naive ulcerative colitis (UC) after mesalamine treatment for 24 months. A review of previous case coincident CMV and UC are explored. Only six previous cases of CMV colitis were reported in patients naive to systemic corticosteroids. We also discuss the relationship between CMV infection and UC as well as the diagnosis, treatment, patient characteristic and outcome. Cytomegalovirus infection should be included in the differential diagnosis of steroid naive UC patients with refractory to conventional non steroids regimen.
[Thai J Gastroenterol 2006; 7(1): 50-54] |