Acute pancreatitis is an inflammatory disease characterized by interstitial edema, inflammatory cell infiltration,
hemorrhages, vacuolization and necrosis of acinar cell necrosis, depending on its severity. Its pathogenic
mechanism to closely associate with tissue injury related to intracellular digestive enzyme activation. Due to these
difficulties, most of our knowledge on pancreatitis is based on research conducted using experimental models of
pancreatitis and have many studies of experimental model of acute pancreatitis. In this review tried to gather the
basic, easy to construct acute pancreatitis models in animals.