Background: Hilar cholangiocarcinoma is the most common cause of malignant biliary obstruction in
Aim: To assess the quality of life (QOL) in patients with hilar cholangiocarcinoma pre- and post-treatment
using the EQ-5D Thai version.
Patients and methods: A total of 261 patients with hilar cholangiocarcinoma prospectively underwent
any one of four treatment modalities (surgery, endoscopic retrograde cholangiopancreatography (ERCP) with biliary
stent placement, percutaneous transbiliary drainage (PTBD), and palliative care). The EQ-5D Thai version was
used for evaluation before and 2-4 weeks after treatment. Pre-treatment and post-treatment utility scores were
Results: The EQ-5D scores in the ERCP with stent group significantly improved after treatment (p=0.049),
especially in the subgroup with adequate biliary drainage (p=0.02). In the surgery and the PTBD groups, the EQ-
5D scores also improved but without statistical significance.
Conclusion: ERCP with adequate biliary drainage improved QOL in patients with hilar